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Nora E. Charles, Ph.D.

 

Assistant Professor

Department of Psychology
The University of Southern Mississippi

 

Period of Service

August 2011 - July 2015

NIDA

Dr. Charles completed her postdoctoral research fellow in the Department of Psychiatry at The University of Texas Health Science Center at San Antonio in the Neurobehavioral Research Laboratory and Clinic (NRLC).

 

Drs Charles and Dougherty control room

In her time with the NRLC, her research focused on family risk for substance use disorder and initiation of substance use and escalation of use from pre- to mid-adolescence.  Major recent findings include determining that the children of people with substance use disorders display increased impulsivity even before they engage in any substance use of their own, and that exposure to stressors during childhood mediates the association between inherited risk for substance abuse and offspring substance use. Together, these results suggest pathways through which having a parent with a substance use disorder may increase risk for substance abuse. Dr. Charles postdoctoral training is funded by a grant from NIDA, Training in Drug Abuse Research: Behavior and Neurobiology (T32-DA031115) and an extramural clinical research loan repayment grant from the National Institutes of Health.

 

Research Project Titles

  • Consequences of Adolescent Substance Use on the Development of Impulse Control (R01-DA026868)
  • Relating Brain Maturation to Impulse Control and Substance Use Involvement (R01-DA033997)

After the NRLC

Vertical logo for The University of Southern Mississippi

 

After her postdoctoral fellowship, Dr. Charles went on to accept a tenure-track Assistant Professor position in the Department of Psychology at the University of Southern Mississippi. 

Dr. Charles lab webpage.

 

 

Selected Publications/Presentations with the NRLC

    Early adolescent trajectories of impulsiveness and sensation seeking in children of fathers with histories of alcohol and other substance use disorders

    Acheson, A., Lake, S. L., Bray, B. C., Liang, Y., Mathias, C. W., Ryan, S. R., Charles, N. E., and Dougherty, D. M. (2016).

    Alcoholism: Clinical & Experimental Research,. 40, 2,622-2,630      PubMed

    Altered developmental trajectories for impulsivity and sensation seeking among adolescent substance users

    Charles, N. E., Ryan, S. R., Bray, B.C., Mathias, C. W., Acheson, A., and Dougherty, D. M. (2016).

    Addictive Behaviors, 60, 235-241     PubMed

    Child problems as a moderator of relations between maternal impulsivity and family environment in a high-risk sample.

    Friedman, C. K., Ryan, S. R., Charles, N. E., Mathias, C. W., Acheson, A., Dougherty, D. M. (2016).

    Substance Use & Misuse, 51, 1264-1273       PubMed

    Pubertal maturation compression and behavioral impulsivity among boys at increased risk for substance use

    Mathias, C. W., Charles, N. E., Liang, Y., Acheson, A., Lake, S. L., Ryan, S. R., Olvera, R. L., and Dougherty, D. M. (2016).

    Addictive Disorders & Their Treatment, 15,  61-73.     PubMed

    Clinical and social/environmental characteristics in a community sample of children with and without family histories of Substance Use Disorder in the San Antonio area: A descriptive study

    Ryan, S. R., Acheson, A., Charles, N. E., Lake, S. L., Hernandez, D. L., Mathias, C. W., and Dougherty, D. M. (2016)

    Journal of Child and Adolescent Substance Abuse, 25, 327-339.

    Family functioning as a mediator of relations between family history of Substance Use Disorder and impulsivity

    Ryan, S. R., Friedman, C. K., Lake, S. L., Mathias, C. W., Charles, N. E., Liang, Y., Acheson, A., and Dougherty, D. M. (2016).

    Addictive Disorders & Their Treatment, 15, 17-24.        PubMed       

    Childhood stress exposure among preadolescents with and without family histories of substance use disorders

    Charles, N. E., Ryan, S. R., Acheson, A., Mathias, C. W., Liang, Y., and Dougherty, D. M.  (2015).

    Psychology of Addictive Behaviors, 29, 192-200.       PubMed

    Increased Pre- and Early-Adolescent Stress in Youth with a Family History of Substance Use Disorder and Early Substance Use Initiation

    Charles, N. E., Mathias, C. W., Acheson, A., Bray, B. C., Ryan, S. R., Lake, S. L., Liang, Y, and Dougherty D. M. (2015).

    Journal of Youth and Adolescence, 44, 1954-1967.       PubMed

    Behavioral impulsivity and risk-taking trajectories across early adolescence in youths with and without family histories of alcohol and other drug use disorders

    Dougherty, D. M., Lake, S. L., Mathias, C. W., Ryan, S. R., Bray, B. C., Charles, N. E., and Acheson, A.  (2015).

    Alcoholism: Clinical & Experimental Research, 39, 1501-1509.     PubMed 

    Aggression as a Predictor of Early Substance Use Initiation among Youth with Family Histories of Substance Use Disorders

    Mathias, C. W., Duffing, T. M., Acheson, A., Charles, N. E., Lake, S. L., Ryan, S. R., Liang, Y., and Dougherty, D. M. (2015). 

    Addictive Disorders & Their Treatment, 14, 230-240.    PubMed

    Exposure to stressors during adolescence differs as a function of family histories of substance use disorders and early-onset substance use

    Charles, N. E., Mathias, C. W., Ryan, S. R., Acheson, A., and Dougherty, D. M. (2015)

    Alcoholism: Clinical & Experimental Research, 39s1, 88a

    Reward impulsivity and rapid progression of puberty in boys at increased risk for substance use problems

    Hernandez, D. L., Mathias, C. W., Charles, N. E., Liang, Y., Acheson, A., Lake, S. L., Ryan, S. R., and Dougherty, D. M. (2015).

    Alcoholism: Clinical & Experimental Research, 39s1, 98a

    Early substance use initiation and aggression among youth from families with substance use disorder

    Mathias, C. W., Duffing, T. M., Acheson, A., Charles, N. E., Lake, S. L., Ryan, S. R., Liang, Y., and Dougherty, D. M. (2015). 

    Alcoholism: Clinical & Experimental Research, 39s1, 132a

    Altered developmental trajectories for impulsiveness and sensation seeking among substance using adolescents

    McCorstin, N. E., Charles, N. E., Mathias, C. W., Ryan, S. R., Acheson, A., and Dougherty, D. M. (2015)

    Alcoholism: Clinical & Experimental Research, 39s1, 98a

    Delay discounting differentiates pre-adolescents at high and low risk for substance use disorders based on family history

    Dougherty, D. M., Charles, N. E., Mathias, C. W., Ryan, S. R., Olvera, R. L., Liang, Y., and Acheson, A.  (2014).

    Drug and Alcohol Dependence, 143, 105-111.      PubMed

    Predictors of initiation and age of onset of substance-use among at-risk adolescents.

    Duffing, T. M., Mathias, C. W., Acheson, A., Lake, S. L, Charles, N.E., Ryan, S. R., and Dougherty, D. M., (2014, January).

    Poster presented at the Fielding Graduate University's Clinical and Media Psychology Winter Poster Session.

    Preadolescents with a family history of substance use disorders demonstrate increased consequence sensitivity impulsivity

    Ford, A., Charles, N. E., Mathias, C. W., Acheson, A., and Dougherty, D.M. (2014, February).

    Poster presented at the 24th annual meeting of the Texas Research Society on Alcoholism, San Antonio, TX.

    Greater exposure to stressful life events during childhood predicts the onset of substance use during early adolescence

    Charles, N. E., Acheson, A., Mathias, C. W., Sheftall, A. H., and Dougherty, D. M. (2014, March).

    Poster presented at the biennial meeting of the Society for Research on Adolescence, Austin, TX

    Greater exposure to stressful life events during childhood predicts the onset of substance use during early adolescence

    Charles, N. E., Acheson, A., Mathias, C. W., Sheftall, A. H., and Dougherty, D. M. (2014, March).

    Symposia presented at the 76th annual meeting of the College on Problems of Drug Dependence, San Juan, Puerto Rico

    P300 amplitude reduction as a predictor of substance use initiation in the context of family history

    Duffing, T. M., Mathias, C. W., Acheson, A., Charles, N. E., Ford, A. N., and Dougherty, D. M. (2014, April).

    Poster presented at annual meeting of the Maryland Psychological Association, Columbia, MD.

    Greater exposure to stressors during preadolescence predicts early adolescent substance use

    Charles, N. E., Mathias, C. W., Acheson, A., & Dougherty, D. M. (2014, May)

    UTHSCSA Department of Psychiatry 2nd Annual Research and Quality Improvement Day 2014, San Antonio, TX

    Preadolescents with a family history of substance use disorders demonstrate increased consequence sensitivity impulsivity

    Ford, A., Charles, N. E., Mathias, C. W., Acheson, A., & Dougherty, D. M.  (2014, May)

    UTHSCSA Department of Psychiatry 2nd Annual Research and Quality Improvement Day 2014, San Antonio, TX

    Multimodal assessment of the development of impulsivity in adolescents with and without family histories of substance use disorders

    Newhouse, J., Charles, N. E., Mathias, C. W., Acheson, A., & Dougherty, D. M. (2014, May)

    UTHSCSA Department of Psychiatry 2nd Annual Research and Quality Improvement Day 2014, San Antonio, TX

    At-risk preadolescents who initiate early adolescent substance use have increased attentional impulsivity but no differences in sensation-seeking

    Hernandez, D. L., Charles, N. E., Mathias, C. W., Acheson, A., and Dougherty, D. M. (2014, June).

    Poster presented at the 24th annual meeting of the Texas Research Society on Alcoholism, San Antonio, TX.

    At-risk preadolescents who initiate early adolescent substance use have increased attentional impulsivity but no differences in sensation seeking

    Hernandez, D. L., Charles, N. E., Mathias, C. W., Acheson, A., and Dougherty, D. M. (2014, June).

    Poster presented at the 37th annual meeting of the Research Society on Alcoholism, Bellevue, Washington.

    Changes in self-reported impulsivity and sensation seeking from age 10 to 15 in youth with and without family histories of substance use disorders

    McCorstin, S., Charles, N. E., Mathias, C. W., Acheson, A., and Dougherty, D. M. (2014, February).

    Poster presented at the 24th annual meeting of the Texas Research Society on Alcoholism, San Antonio, TX.

    Multimodal Assessment of the development of impulsivity in adolescents with and without family histories of substance use disorders

    Newhouse, J., Charles, N. E., Mathias, C.,W., Acheson, A., and Dougherty, D. M. (2014, February).

    Poster presented at the 24th annual meeting of the Texas Research Society on Alcoholism, San Antonio, TX.

    A description of familial and environmental characteristics among children at risk for substance use

    Ryan, S. R., Hernandez, D. L., Charles, N. E., Acheson, A., Mathias, C. W. and Dougherty, D. M. (2014, August).

    Poster accepted for presentation at the 122nd annual meetings of the American Psychological Association, Washington, DC.

    Motivational value and salience of images of infants.

    Charles, N. E., Alexander, G. M., Saenz, J.  (2013).

    Evolution and Human Behavior, 34, 373-381

    Exposure to stressful life events mediates the relation between family history of substance abuse and childhood adjustment

    Charles, N.E., Acheson, A., Mathias, C.W., and Dougherty, D.M. (2013, June)

    Poster presented at the 75th annual meeting of the College on Problems of Drug Dependence, San Diego, CA.

    Exposure to stressful life events mediates the relation between family history of substance abuse and childhood adjustment.

    Charles, N. E., Acheson, A., Mathias, C. W., and Dougherty, D. M. (2013, June)

    Poster presented at the 1st annual UTHSCSA Psychiatry Resident Research and Quality Improvement Day, San Antonio, TX

    Impulsivity, attention, memory, and decision-making among adolescent marijuana users

    Dougherty, D. M., Mathias, C. W., Dawes, M. A., Furr, R. M., Charles, N. E., Liguori, A., Shannon, E. E., Acheson, A.  (2013).

    Psychopharmacology, 226, 307-319.      PubMed     Free in PMC

    Reduced Amplitude P3 and Externalizing Psychopathology in Young Adolescents at-risk for Developing Substance Use Disorders.

    Ford, A. N., Charles, N. E., Mathias, C. W., Acheson, A. and Dougherty, D. M.  (2013, June)

    Poster presented at the 1st annual UTHSCSA Psychiatry Resident Research and Quality Improvement Day, San Antonio, TX

    Children with Family Histories of Alcohol Use Disorders Show a Difference in Delay Discounting and Behavioral Functioning.

    Hernandez, D. L., Charles, N. E., Acheson, A., Mathias, C. W., and Dougherty, D. M.  (2013, June)

    Poster presented at the 1st annual UTHSCSA Psychiatry Resident Research and Quality Improvement Day, San Antonio, TX

    Children with family histories of alcohol use disorders show greater discounting of delayed rewards

    Vela-Gude, M., Charles, N. E., Acheson, A., Mathias, C. W., and Dougherty, D. M. (2013, June).

    Poster presented at the 1st annual UTHSCSA Psychiatry Resident Research and Quality Improvement Day, San Antonio, TX

    Children with Family Histories of Alcohol Use Disorders Show Increased Behavioral Problems.

    Xu, A., Charles, N. E., Acheson, A., Mathias, C. W., and Dougherty, D. M.  (2013, June).

    Poster presented at the 1st annual UTHSCSA Psychiatry Resident Research and Quality Improvement Day, San Antonio, TX

    The effects of a family history of substance use disorders on different components of impulsivity in children

    Charles, N.E., Acheson, A., Mathias, C.W., and Dougherty, D.M. (2013, June)

    Symposia presented at the 5th annual meeting of the Behavior, Biology, and Chemistry (BBC) UTHSCSA, San Antonio, TX

    Reduced amplitude P3 and externalizing psychopathology in young adolescents at risk for developing substance use disorders
    Ford, A.N, Charles, N.E., Mathias, C.W., Acheson, A., and Dougherty, D.M. (2013, February)

    Poster presented at the 23rd annual meeting of the Texas Research Society on Alcoholism, Austin, TX.

    Children with family histories of alcohol use disorders show a difference in delay discounting and behavioral function

    Hernandez, D.L.,Ford, A.N., Charles, N.E., Mathias, C.W., Acheson, A., and Dougherty, D.M. (2012, June)
    Poster presented at the 36th annual meeting of the Research Society on Alcoholism, Orlando, FL

    Children with family histories of alcohol use disorders show greater discounting of delayed rewards

    Vela-Gude, M., Charles, N. E., Acheson, A., Mathias, C. W., and Dougherty, D. M. (2013, February)

    Poster presented at the 23rd annual meeting of the Texas Research Society on Alcoholism, Austin, TX.

    Children with family histories of alcohol use disorders show increased behavioral problems

    Xu, A., Charles, N. E., Acheson, A., Mathias, C. W., and Dougherty, D. M. (2013, February)

    Poster presented at the 23rd annual meeting of the Texas Research Society on Alcoholism, Austin, TX.

    Psychopathic traits and their association with adjustment problems in girls.

    Charles, N. E., Acheson, A., Mathias, C. W., Furr, R. M., Dougherty, D. M.  (2012).    

    Behavioral Sciences and the Law, 30, 631-642.       PubMed     Free in PMC

    Comparing the detection of transdermal and breath alcohol concentrations during periods of alcohol consumption ranging from moderate drinking to binge drinking.

    Dougherty DM, Charles NE, Acheson A, John S, Furr RM, Hill-Kapturczak N. (2012).

    Experimental and Clinical Psychopharmacology, 20, 373-381.     PubMed

    Children with a family history of alcohol and other drug use disorders show increased discounting of delayed monetary rewards
    Acheson, A., Hernandez D.L, Ford, A.N., Charles, N.E., Mathias, C.W., and Dougherty, D.M. (2012, February).

    Poster presented at the 22nd annual meeting of the Texas Research Society on Alcoholism, College Station, TX

    Differential performance across multiple measures of impulsivity among children with family histories of substance use disorders

    Acheson, A., Charles, N.E., Mathias, C.W., and Dougherty, D.M. (2012, June).

    Poster presented at the 74th annual meeting of the College on Problems of Drug Dependence, Palm Springs, CA

    Children with family histories of alcohol and other drug use disorders show increased discounting of delayed rewards
    Acheson, A.,
    Hernandez, D.L., Ford, A.N.,
    Charles, N.E., Mathias, C.W., and Dougherty, D.M. (2012, June)

    Poster presented at the 35th annual meeting of the Research Society on Alcoholism, San Francisco, CA

    Parental impulsivity is related to preadolescents' stressful life events

    Charles, N.E., Acheson, A., Mathias, C.W., and Dougherty, D.M. (2012, February).

    Poster presented at the 22nd annual meeting of the Texas Research Society on Alcoholism, College Station, TX

    Parental impulsivity is related to preadolescents' stressful life events

    Charles, N.E., Acheson, A., Mathias, C.W., and Dougherty, D.M. (2012, March).

    Poster presented at the annual meeting of the Society for Personality Assessment, Chicago, IL

    Comparing transdermal and breath alcohol concentration readings during periods of alcohol consumption from moderate to binge drinking

    Dougherty, D.M., Cates, S.E., Charles, N.E., Acheson, A., John, S., Furr, R. M., Hill-Kapturczak, N. (2012, June).

    Poster presented at the 35th annual meeting of the Research Society on Alcoholism, San Francisco, CA

    Children with family histories of alcohol and other drug use disorders experience increased childhood adversity

    Hernandez, D.L., Ford, A.N., Charles, N.E., Mathias, C.W., Acheson, A., and Dougherty, D.M. (2012, June)

    Poster presented at the 35th annual meeting of the Research Society on Alcoholism, San Francisco, CA

    Hispanic children at risk for developing alcohol and drug use disorders have increased externalizing behaviors

    Ford, A.N., Hernandez, D.L., Charles, N.E., Mathias, C.W., Acheson, A., and Dougherty, D.M. (2012, June)
    Poster presented at the 35th annual meeting of the Research Society on Alcoholism, San Francisco, CA

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