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Donald M. Dougherty, Ph.D.

Dougherty Office

The William & Marguerite Wurzbach Distinguished Professor

Director, Neurobehavioral Research Division

Deputy Chair for Research, Department of Psychiatry

The University of Texas Health Science Center at San Antonio

Biographical Sketch

Dr. Dougherty is the William and Marguerite Wurzbach Distinguished Professor and Director of the Neurobehavioral Research Division within the Department of Psychiatry at The University of Texas Health Science Center at San Antonio. He also serves as the Director of the Neurobehavioral Research Laboratory and Clinic (NRLC) and Co-Director of the Research Residency Program. He completed his graduate training in Psychology at Ohio University and then held a National Institute for Drug Abuse sponsored postdoctoral research fellowship at The University of Texas Health Science Center at Houston (UTHSCH). After completing his training, Dr. Dougherty joined the faculty at UTHSCH, where the NRLC group was founded. After 12 years at UTHSCH, Dr. Dougherty and the NRLC research team moved to Wake Forest University Health Sciences in Winston-Salem, NC where Dr. Dougherty became Professor and Vice Chair for Research in the Department of Psychiatry. During his tenure as Vice Chair for Research, the Department of Psychiatry made significant progress toward the development of an interdisciplinary translational research program, which was evidenced by substantial increases in support from the National Institutes of Health and private donors. Seeing a great potential for expanding a translational research program to include interactions with community leaders within San Antonio, Dr. Dougherty and the NRLC research team returned to The University of Texas Health Sciences System in 2007. Dr. Dougherty's research interests are focused on understanding impulsive behaviors, with primary emphasis on problems associated with drug abuse and suicidality. Current projects include examining how drug abuse and early stressful life events adversely affect adolescent development of impulse control, and their relationship to the development of other adolescent psychopathology. Additionally, his interests include the identification of biological and behavioral risk factors for child and adult psychopathology. As an extension of this research, Dr. Dougherty and his colleagues have developed behavioral software paradigms for objectively assessing underlying mechanisms of different types of impulsive behavior. These paradigms have been validated in numerous studies and are freely available to other researchers. The long-term goals of the NRLC are to use information gathered from their research to inform the development of better treatment and community-based substance abuse prevention programs.

Research Interests

  • Adolescent Development of Impulse Control
  • Substance Use Initiation and Abuse
  • Developmental Course of Suicidal Behaviors
  • Identification and Measurement of Impulsive and Aggressive Behaviors
  • Effects of Alcohol and Other Drugs of Abuse on Impulsive and Aggressive Behaviors
  • Therapeutic Pharmacotherapy and their Effect on Behavioral Processes
  • L-Tryptophan Depletion and Loading Methodologies
  • Biological and Behavioral Markers and Neuroendocrine Challenge Procedures
  • Behavioral Studies of Functional Magnetic Resonance Imaging
  • Evaluation of Gender Differences in the above areas
  • Development of Software and Paradigms for Objective Assessment of Behavior

Education

Year Degree Major Institution
1995 Fellowship Substance Abuse The University of Texas Medical School
1992 Ph.D. Experimental Psychology Ohio University
1990 M.S. Experimental Psychology Ohio University
1985 B.S. Psychology Bridgewater College

Citation Record

  • 6449 Times Cited
  • 46 Citations per Publication
  • 40 h-index
Citations per Year

Presentations/Publications with the NRLC

  • Laboratory measures of impulsivity.

    Dougherty, D. M., Mathias, C. W., Marsh, D. M., Jagar, A. A. (2005).

    Behavior Research Methods, 37, 82-90. PubMed Icon

  • Predictors of initiation and age of onset of substance-use among at-risk adolescents.

    Duffing, T. M., Mathias, C. W., Acheson, A., Lake, S. L, Charles, N.E., Ryan, S. R., and Dougherty, D. M., (2014, January).

    Poster presented at the Fielding Graduate University's Clinical and Media Psychology Winter Poster Session.

  • Using contingency management procedures to reduce at-risk drinking in heavy drinkers

    Dougherty, D. M., Lake, S. L., Hill-Kapturczak, N., Liang, Y., Karns, T. E., Mullen, J., and Roache, J. D. (2015).

    Alcoholism: Clinical and Experimental Research, 39, 109-121. PubMed Icon

  • Reliability estimates for the Immediate and Delayed Memory Tasks.

    Mathias, C. W., Marsh, D. M., and Dougherty, D. M. (2002).

    Perceptual and Motor Skills, 95, 559-569. PubMed Icon

  • The correspondence between transdermal alcohol monitoring and daily self-reported alcohol consumption

    Karns-Wright, T. E., Dougherty, D. M., Hill-Kapturczak, N., Mathias, C. W., and Roache, J. D. (in press).

    Addictive Behaviors.

  • Reproducibility of tract-based white matter microstructural measures using the ENIGMA-DTI protocol

    Acheson, A., Witjtenburg, S. A., Rowland, L. R., Winkler, A., Mathias, C. W., Hong, L. E., Jahanshad, N., Patel, B., Thompson, P.M., McGuire, S.A., Sherman, P. M., Kochunov, P., and Dougherty, D. M. (2017).

    Brain and Behavior, 7, 1-10. PubMed Icon

  • Preadolescent sensation seeking and early adolescent stress relate to at-risk adolescents’ substance use by age 15

    Charles, N. E., Mathias, C. W., Acheson, A., and Dougherty, D. M. (2017).

    Addictive Behaviors, 69, 1-7. PubMed Icon

  • Early adolescent trajectories of impulsiveness and sensation seeking in children of fathers with histories of alcohol and other substance use disorders

    Acheson, A., Lake, S. L., Bray, B. C., Liang, Y., Mathias, C. W., Ryan, S. R., Charles, N. E., and Dougherty, D. M. (2016).

    Alcoholism: Clinical & Experimental Research,. 40, 2,622-2,630 PubMed Icon

  • Assessment of the human kynurenine pathway: Comparisons and clinical implications of ethnic and gender differences in plasma tryptophan, kynurenine metabolites, and enzyme expressions at baseline and after acute tryptophan loading and depletion.

    Badawy, A. A-B., Dougherty, D. M. (2016).

    International Journal of Tryptophan Research, 9, 31-49. PubMed Icon

  • Altered developmental trajectories for impulsivity and sensation seeking among adolescent substance users

    Charles, N. E., Ryan, S. R., Bray, B.C., Mathias, C. W., Acheson, A., and Dougherty, D. M. (2016).

    Addictive Behaviors, 60, 235-241 PubMed Icon

  • Acute effects of methylphenidate on impulsivity and attentional behavior in Comorbid ADHD and Conduct Disorder

    Dougherty, D. M., Olvera, R. L., Acheson, A., Hill-Kapturczak, N., Ryan, S. R., and Mathias, C. W. (2016).

    Journal of Adolescence, 53, 222-230. PubMed Icon

  • Child problems as a moderator of relations between maternal impulsivity and family environment in a high-risk sample.

    Friedman, C. K., Ryan, S. R., Charles, N. E., Mathias, C. W., Acheson, A., Dougherty, D. M. (2016).

    Substance Use & Misuse, 51, 1264-1273 PubMed Icon

  • Characterization of the pharmacokinetics of Phosphatidylethanol 16:0/18:1 and 16:0/18:2 in human whole blood after alcohol consumption in a clinical laboratory study.

    Javors, M. A., Hill-Kapturczak, N., Roache, J. D., Karns-Wright, T. E., and Dougherty, D. M. (2016).

    Alcoholism: Clinical and Experimental Research, 40, 1228-1234. PubMed Icon

  • Pubertal maturation compression and behavioral impulsivity among boys at increased risk for substance use

    Mathias, C. W., Charles, N. E., Liang, Y., Acheson, A., Lake, S. L., Ryan, S. R., Olvera, R. L., and Dougherty, D. M. (2016).

    Addictive Disorders & Their Treatment, 15, 61-73. PubMed Icon

  • Behavioral impulsivity does not predict naturalistic alcohol consumption or treatment outcomes

    Mullen, J., Mathias, C. W., Karns, T. E., Liang, Y., Hill-Kapturczak, N., Roache, J. D. Lamb, R. J., and Dougherty, D. M. (2016).

    Addictive Disorders & Their Treatment, 15, 120-128. PubMed Icon

  • Clinical and social/environmental characteristics in a community sample of children with and without family histories of Substance Use Disorder in the San Antonio area: A descriptive study

    Ryan, S. R., Acheson, A., Charles, N. E., Lake, S. L., Hernandez, D. L., Mathias, C. W., and Dougherty, D. M. (2016).

    Journal of Child and Adolescent Substance Abuse, 25, 327-339.

  • Family functioning as a mediator of relations between family history of Substance Use Disorder and impulsivity

    Ryan, S. R., Friedman, C. K., Lake, S. L., Mathias, C. W., Charles, N. E., Liang, Y., Acheson, A., and Dougherty, D. M. (2016).

    Addictive Disorders & Their Treatment, 15, 17-24. PubMed Icon

  • Functional activation and effective connectivity differences in adolescent marijuana users performing a simulated gambling task

    Acheson, A., Ray, K., Hines, C., Li K., Dawes, M. A., Mathias, C. W., Dougherty, D. M., and Laird, A. (2015).

    Journal of Addiction, 2015 (783106), 1-11. PubMed Icon PubMed Central - Free Full Text Icon

  • Striatal activity and reduced white matter increase frontal activity in youths with family histories of alcohol and other substance use disorders performing a go/no go task

    Acheson, A., Tagamets, M. A., Winkler, A., Rowland, L. M., Mathias, C. W., Wright, S. N., Hong, L. E., Kochunov. P., and Dougherty, D. M. (2015).

    Brain and Behavior, e00352, doi: 10.1002/brb3.352 PubMed Icon PubMed Central - Free Full Text Icon

  • Standardization of formulations for the acute amino acid depletion and loading tests.

    Badawy, A. A., and Dougherty, D. M. (2015).

    Journal of Psychopharmacology, 29, 363-371. PubMed Icon

  • Increased Pre- and Early-Adolescent Stress in Youth with a Family History of Substance Use Disorder and Early Substance Use Initiation

    Charles, N. E., Mathias, C. W., Acheson, A., Bray, B. C., Ryan, S. R., Lake, S. L., Liang, Y, and Dougherty DM. (2015).

    Journal of Youth and Adolescence, 44, 1954-1967. PubMed Icon PubMed Central - Free Full Text Icon

  • Childhood stress exposure among preadolescents with and without family histories of substance use disorders

    Charles, N. E., Ryan, S. R., Acheson, A., Mathias, C. W., Liang, Y., and Dougherty, D. M. (2015).

    Psychology of Addictive Behavior, 29, 192-200. PubMed Icon PubMed Central - Free Full Text Icon

  • Transdermal alcohol concentration data collected during a contingency management program to reduce at-risk drinking

    Dougherty, D. M., Karns, T. E., Mullen, J., Liang, Y., Lake, S. L., Roache, J. D., and Hill-Kapturczak, N. (2015).

    Drug and Alcohol Dependence, 148, 77-84. PubMed Icon

  • Behavioral impulsivity and risk-taking trajectories across early adolescence in youths with and without family histories of alcohol and other drug use disorders

    Dougherty, D. M., Lake, S. L., Mathias, C. W., Ryan, S. R., Bray, B. C., Charles, N. E., and Acheson, A. (2015).

    Virtual Issue on Risk Factors for Adolescent Drinking PubMed Icon PubMed Central - Free Full Text Icon

  • Effects of tryptophan depletion and a simulated alcohol binge on impulsivity.

    Dougherty, D. M., Mullen, J., Hill-Kapturczak, N., Liang, Y., Karns, T. E., Lake, S. L., Mathias, C. M., and Roache, J. D. (2015).

    Experimental and Clinical Psychopharmacology, 23, 109-121. PubMed Icon PubMed Central - Free Full Text Icon

  • Accounting for sex-related differences in the estimation of breath alcohol levels using transdermal alcohol monitoring

    Hill-Kapturczak, N., Roache, J. D., Liang, Y., Karns, T. E., Cates, S. E., and Dougherty, D. M. (2015).

    Psychopharmacology, 232, 115-123. PubMed Icon PubMed Central - Free Full Text Icon

  • Aggression as a Predictor of Early Substance Use Initiation among Youth with Family Histories of Substance Use Disorders

    Mathias, C. W., Duffing, T. M., Acheson, A., Charles, N. E., Lake, S. L., Ryan, S. R., Liang, Y., and Dougherty, D. M. (2015).

    Addictive Disorders & Their Treatment, 14, 230-240. PubMed Icon PubMed Central - Free Full Text Icon

  • Feasibility of a computer-assisted alcohol screening, brief intervention and referral to treatment program for DWI offenders

    Mullen, J., Ryan, S. R., Mathias, C. W., and Dougherty, D. M. (2015).

    Addiction Science & Clinical Practice, 10, 1-10. Atlas of Science

  • Treatment needs of driving while intoxicated offenders: The need for a multi-modal approach to treatment

    Mullen, J., Ryan, S. R., Mathias, C. W., and Dougherty, D. M. (2015).

    Traffic Injury Prevention, 16, 367-644. PubMed Icon PubMed Central - Free Full Text Icon

  • Using transdermal alcohol monitoring to detect low-level drinking

    Roache, J. D., Karns, T. E., Hill-Kapturczak, N., Mullen, J., Liang, Y., Lamb, R. J., and Dougherty, D. M. (2015).

    Alcoholism: Clinical & Experimental Research, 39, 1120-1127. PubMed Icon PubMed Central - Free Full Text Icon

  • Increased forebrain activations in youths with family histories of alcohol and other Substance Use Disorders performing a Go/No Go Task

    Acheson, A., Tagaments, M., Winkler, A., Rowland, L. M., Mathias, C. W., Write, S. N., Hong, L. E., Kochunov, P., and Dougherty, D. M. (2014).

    Alcoholism: Clinical and Experimental Research, 38, 2944-2951. PubMed Icon PubMed Central - Free Full Text Icon

  • Mechanisms of the pellagragenic effect of leucine: stimulation of hepatic tryptophan oxidation by administration of branched-chain amino acids to healthy human volunteers and the role of plasma free tryptophan and total kynurenines.

    Badawy, A. A., Lake, S. L., Dougherty, D. M. (2014).

    International Journal of Tryptophan Research, 7, 23-32. PubMed Icon PubMed Central - Free Full Text Icon

  • Delay discounting differentiates pre-adolescents at high and low risk for substance use disorders based on family history

    Dougherty, D. M., Charles, N. E., Mathias, C. W., Ryan, S. R., Olvera, R. L., Liang, Y., and Acheson, A. (2014).

    Drug and Alcohol Dependence, 143, 105-111. PubMed Icon PubMed Central - Free Full Text Icon

  • Use of continuous transdermal alcohol monitoring during a contingency management procedure to reduce excessive alcohol use.

    Dougherty, D. M., Hill-Kapturczak, N., Liang, Y., Karns, T. E., Cates, S. E., Lake, S. L., Mullen, J., and Roache, J. D. (2014).

    Drug and Alcohol Dependence, 142, 301-306. PubMed Icon PubMed Central - Free Full Text Icon

  • Ethical considerations in adolescent drug research, a response to “Conflicting ethics of confidentiality in adolescent drug research”

    Dougherty, D. M., Hill-Kapturczak, N., Ryan, S. R., Mathias, C. W., Dawes, M. A., Acheson, A., Charles, N. E., Furr, M. A., and Liguori, A. (2014).

    Psychopharmacology, 231(8), 1433-1435. DOI: 10.1007/s00213-013-3183-9 PubMed Icon

  • Stress, substance abuse, and addiction

    Duffing, T. M., Greiner, S. G., Mathias, C. W., Dougherty, D. M. (2014).

    Current Topics in Behavioral Neuroscience, 18, 237-263. PubMed Icon

  • Do variable rates of alcohol drinking alter the ability to use transdermal alcohol monitors to estimate peak breath alcohol and total number of drinks?

    Hill-Kapturczak, N., Lake, S.L., Roache, J.D., Cates, S.E., Liang, Y., Dougherty, D.M. (2014).

    Alcoholism: Clinical and Experimental Research, 38, :2517-2522. PubMed Icon PubMed Central - Free Full Text Icon

  • Accounting for sex-related differences in the estimation of breath alcohol concentrations using transdermal alcohol monitoring

    Hill-Kapturczak, N., Roache, J. D., Liang, Y., Karns, T. E., Cates, S. E., Dougherty, D. M. (2014).

    Psychopharmacology, 232, 115-123.. PubMed Icon PubMed Central - Free Full Text Icon

  • Problem identification and community assessment of DWI needs for Bexar County, Texas

    Mathias, C. W., Ryan, S. R., Mullen, J., Lake, S. L., Brown, P. C., Adams, V., Villafranca, C., and Dougherty, D. M. (2014).

    Center for Medicare & Medicaid Services report 085144601.2.6: University of Texas Health Science Center San Antonio.

  • Impulsivity, attention, memory, and decision-making among adolescent marijuana users

    Dougherty, D. M., Mathias, C. W., Dawes, M. A., Furr, R. M., Charles, N. E., Liguori, A., Shannon, E. E., Acheson, A. (2013).

    Psychopharmacology, 226, 307-319. PubMed Icon PubMed Central - Free Full Text Icon

  • Adolescent attachment security, family functioning, and suicide attempts

    Sheftall, A. H., Mathias, C. W., Furr, R. M., and Dougherty, D. M. (2013).

    Attachment and Human Development, 15, 368-383. PubMed Icon PubMed Central - Free Full Text Icon

  • Acquisition of rater agreement for the Stressful Life Events Schedule

    James, L. M., Mathias, C. W., Bray, B. C., Cates, S. E., Farris, S. J., Dawes, M. A., Hill-Kapturczak, N., and Dougherty, D. M. (2013)

    Journal of Alcoholism and Drug Dependence, 1:125, 1-5.

  • Continuous objective monitoring of alcohol use: Twenty-first century measurement using transdermal sensors.

    Leffingwell, T. R., Cooney, N. J., Murphy, J. G., Luczak, S., Rosen, G., Dougherty, D. M., Barnett, N. P. (2013).

    Alcoholism: Clinical and Experimental Research, 37, 16-22 PubMed Icon

  • What is the harm in asking about suicidal ideation?

    Mathias, C. W., Furr, R. M., Sheftall, A. H., Hill-Kapturczak, N., Crum, P. and Dougherty, D. M. (2012).

    Suicide and Life-Threatening Behavior, 42, 341-351. PubMed Icon PubMed Central - Free Full Text Icon

  • Psychopathic traits and their association with adjustment problems in girls.

    Charles, N. E., Acheson, A., Mathias, C. W., Furr, R. M., Dougherty, D. M. (2012).

    Behavioral Sciences and the Law, 30, 631-642. PubMed Icon PubMed Central - Free Full Text Icon

  • Comparing the detection of transdermal and breath alcohol concentrations during periods of alcohol consumption ranging from moderate drinking to binge drinking.

    Dougherty, D. M., Charles, N. E., Acheson, A., John, S., Furr, R.M., Hill-Kapturczak, N. (2012).

    Experimental and Clinical Psychopharmacology, 20, 373-381. PubMed Icon PubMed Central - Free Full Text Icon

  • Intolerance to delayed reward in girls with multiple suicide attempts.

    Mathias, C. W., Dougherty, D. M., James, L. M., Richard, D. M., Dawes, M. A., Acheson, A., and Hill-Kapturczak, N. (2011).

    Suicide and Life-Threatening Behavior, 41, 277-286. PubMed Icon PubMed Central - Free Full Text Icon

  • Failure to sustain prepulse inhibition in adolescent marijuana users.

    Mathias, C. W., Blumenthal, T. D., Dawes, M. A., Liguori, A., Richard, D. M., Bray, B., Tong, W., and Dougherty, D. M. (2011).

    Drug and Alcohol Dependence, 116, 110-116. PubMed Icon PubMed Central - Free Full Text Icon

  • Adults with a family history of alcohol related problems are more impulsive on measures of response initiation and response inhibition.

    Acheson, A., Richard, D. M., Mathias, C. W., and Dougherty, D. M. (2011).

    Drug and Alcohol Dependence, 117, 198-203. PubMed Icon PubMed Central - Free Full Text Icon

  • Suicide and life-events

    Busch, A. M., Cornette, M. M., Mathias, C. W., Marsh, D. M., and Dougherty, D. M. (2011). In A. Shrivastava, M. T. Kimbrell, D. Lester (Eds.)

    Suicide from a Global Perspective: Psychosocial Approaches (pp. 27-32). Nova Science Publishers Inc: Hauppauge, NY.

  • Cognition and suicide

    Cornette, M. M., Mathias, C. W., Marsh, D. M., deRoon-Cassini, T. A., and Dougherty, D. M. (2011). In A. Shrivastava, M. T. Kimbrell, D. Lester (Eds.)

    Suicide from a Global Perspective: Psychosocial Approaches (pp. 3-10). Nova Science Publishers Inc: Hauppauge, NY.

  • Effects of acute tryptophan depletion on three types of behavioral impulsivity.

    Dougherty, D. M., Richard, D. M., James, L. M., and Mathias, C. W. (2010).

    International Journal of Tryptophan Research, 3, 99-111. PubMed Icon PubMed Central - Free Full Text Icon

  • Cognitive impairments in adolescent cannabis abusers are related to THC levels.

    Shannon, E., Mathias, C. W., Dougherty, D. M., and Liguori, A. (2010).

    Addictive Behaviors and Their Treatment 9, 158-163.

  • Specificity of the acute Tryptophan and Tyrosine plus Phenylalanine depletion and loading tests Part I. Review of biochemical aspects and poor specificity of current amino acid formulations.

    Badawy, A. A.-B., Dougherty, D. M., and Richard, D. M. (2010).

    International Journal of Tryptophan Research, 3, 23-34. PubMed Icon PubMed Central - Free Full Text Icon

  • Specificity of the acute Tryptophan and Tyrosine plus Phenylalanine depletion and loading tests Part II. Normalisation of the Tryptophan and Tyrosine plus Phenylalanine to competing amino acid ratios in a new control formulation.

    Badawy, A. A.-B., Dougherty, D. M., and Richard, D. M. (2010).

    International Journal of Tryptophan Research, 3, 35-47. PubMed Icon PubMed Central - Free Full Text Icon

  • Impulsivity and clinical symptoms among adolescents with non-suicidal self-injury with or without attempted suicide.

    Dougherty, D. M., Mathias, C. W., Marsh-Richard, D. M., Prevette, K. N., Dawes, M. A., Hatzis, E. S., Palmes, G., and Nouvion, S. O. (2009)

    Psychiatry Research, 169, 22-27 PubMed Icon PubMed Central - Free Full Text Icon

  • Distinctions in behavioral impulsivity: Implications for substance abuse research.

    Dougherty, D. M., Mathias, C. W., Marsh-Richard, D. M., Furr, R. M., Nouvion, S. O., and Dawes, M. A. (2009)

    Addictive Disorders and Their Treatment, 8, 61-73. PubMed Icon PubMed Central - Free Full Text Icon

  • Fifty years of the Barratt Impulsiveness Scale: An update and review.

    Stanford, M. S., Mathias, C. W., Dougherty, D. M., Lake, S. L., Anderson, N. E., and Patton, J. H.. (2009).

    Personality and Individual Differences, 47, 385-395.

  • Drinking histories in alcohol-use-disordered youth: preliminary findings on relationships to platelet serotonin transporter expression with genotypes of the serotonin transporter.

    Dawes, M. A., Roache, J. D., Javors, M. A., Bergeson, S. E., Richard, D. M., Mathias, C. W., Ait-Daoud, N., Dougherty, D. M., and Johnson, B. A. (2009)

    Journal of Studies on Alcohol and Drugs, 70, 899-907. PubMed Icon PubMed Central - Free Full Text Icon

  • Activation of liver Tryptophan Pyrolase mediates the decrease in Tryptophan availability to the brain after acute alcohol consumption in normal subjects.

    Badawy A. A.-B, Dougherty D. M., Marsh-Richard, D. M., and Steptoe, A. (2009).

    Alcohol and Alcoholism, 44, 267-271. PubMed Icon PubMed Central - Free Full Text Icon

  • The Adaptive Visual Analog Scales (AVAS): A modifiable software program for the creation, administration, and scoring of visual analog scales.

    Marsh-Richard, D. M., Hatzis, E. S., Mathias, C. W., Venditti, N., and Dougherty, D. M. (2009).

    Behavior Research Methods, 41, 99-106. PubMed Icon PubMed Central - Free Full Text Icon

  • Candidate endophenotypes for genetic studies of suicidal behavior.

    Mann, J. J., Arango, V. A., Avenevoli, S., Champagne, F. A., Clayton, P., Currier, D., Dougherty, D. M., et al. (2009).

    Biological Psychiatry, 65, 556-563 PubMed Icon PubMed Central - Free Full Text Icon

  • Differentiating impulsive and premeditated aggression: Self and informant perspectives among adolescents with personality pathology.

    Gauthier, K. J., Furr, R. M., Mathias, C. W., Marsh-Richard, D. M., and Dougherty, D. M. (2009).

    Journal of Personality Disorders, 23, 76-84 PubMed Icon PubMed Central - Free Full Text Icon

  • L-tryptophan: Basic metabolic functions, behavioral research, and therapeutic indications.

    Marsh-Richard, D. M., Dawes, M. A.., Mathias, C. W., Acheson, A., Hill-Kapturczak, N., and Dougherty, D. M. (2009).

    International Journal of Tryptophan Research, 2, 45-60. PubMed Icon PubMed Central - Free Full Text Icon

  • Adolescent suicidal behavior and substance use: Developmental mechanisms

    Dawes, M. A., Mathias, C. W., Richard, D. M., Hill-Kapturczak, N., and Dougherty, D. M. (2008).

    Substance Abuse: Research and Treatment, 2, 13-28 PubMed Icon PubMed Central - Free Full Text Icon

  • Behavioral measures of impulsivity and the law.

    Mathias, C. W., Marsh-Richard, D. M., and Dougherty, D. M. (2008).

    Behavioral Sciences and the Law, 26, 691-707. PubMed Icon PubMed Central - Free Full Text Icon

  • A test of alcohol dose effects on multiple behavioral measures of impulsivity.

    Dougherty, D. M., Marsh-Richard, D. M., Hatzis, E. S., Nouvion, S. O., and Mathias, C. W. (2008).

    Drug and Alcohol Dependence, 96, 111-120. PubMed Icon PubMed Central - Free Full Text Icon

  • Prospective study of cannabis withdrawal in cannabis-using adolescents..

    Dawes, M. A., Richard, D. M., Mathias, C. W., and Dougherty, D. M. (2008).

    Journal of the American Academy of Child and Adolescent Psychiatry, 47, 1095-1096. PubMed Icon PubMed Central - Free Full Text Icon

  • Comparison of 50g and 100g L-tryptophan depletion and loading formulations for altering 5-HT synthesis:  Pharmacokinetics, side effects, and mood states.

    Dougherty, D. M., Marsh-Richard, D. M., Mathias, C. W., Hood, A. J., Addicott, M. A., Moeller, F. G., Morgan, C. J., and Badawy, A. A.-B. (2008).

    Psychopharmacology, 198, 431-445. PubMed Icon PubMed Central - Free Full Text Icon

  • The biphasic effects of alcohol: Comparison of subjective and objective measures of stimulation, sedation, and physical activity.

    Addicott, M. A., Marsh-Richard, D. M., Mathias, C. W., and Dougherty, D. M. (2007).

    Alcoholism: Clinical and Experimental Research, 31, 1883-1890 PubMed Icon

  • The acute tryptophan depletion and loading tests: Specificity issues.

    Badawy, A. A.-B., Morgan, C. J., Dougherty, D. M., Marsh, D. M., Mathias, C. W., Jagar, A. A., Addicott, M. A., and Moeller, F. G. (2007).

    International Congress Series, 1304C, 159-166.

  • Assessment of the kynurenine pathway in humans 1. Normal plasma values, ethnic differences, and their clinical implications.

    Badawy, A. A.-B., Morgan, C. J., Turner, J. A., Dougherty, D. M., Marsh, D. M., Mathias, C. W., Addicott, M. A., and Jagar, A. A. (2007).

    International Congress Series, 1304C, 335-343.

  • Impulsive and premeditated subtypes of aggression in Conduct Disorder: Differences in time estimation.

    Dougherty, D. M., Dew, R. E., Mathias, C. W., Marsh, D. M., Addicott, M. A., and Barratt, E. S. (2007).

    Aggressive Behavior, 33, 574-582 PubMed Icon

  • The effects of alcohol on laboratory-measured impulsivity after L-Tryptophan depletion or loading.

    Dougherty, D. M., Marsh, D. M., Mathias, C. W., Dawes, M. A., Bradley, D. M., Morgan, C. J., and Badawy, A. A.-B. (2007).

    Psychopharmacology, 193, 137-150. PubMed Icon

  • Behavioral impulsivity in adolescents with Conduct Disorder who use Marijuana.

    Dougherty, D. M., Mathias, C. W., Liguori, A., Marsh, D. M. Dawes, M. A. and Moeller, F. G. (2007).

    Addictive Disorders and Their Treatment, 6, 43-50.

  • Personality judgment and personality pathology: Self-other agreement in adolescents with Conduct Disorder.

    Furr, R. M., Dougherty, D. M., Marsh, D. M., and Mathias, C. W. (2007).

    Journal of Personality, 75, 629-662. PubMed Icon

  • Suicidal and nonsuicidal self-harm behaviors in adolescent substance use disorders.

    Goldston, D. B., Daniel, S. S., Mathias, C. W., and Dougherty, D. M. (2007).

    In Y. Kaminer and O. Bukstein (Eds.), Adolescent Substance Abuse: Psychiatric Comorbidity and High Risk Behaviors (pp. 323-354).
    Routledge, Taylor & Francis Group: New York, New York

  • The relationship of inattentiveness, hyperactivity, and psychopathy among adolescents.

    Mathias, C. W., Furr, R. M., Daniel, S. S., Marsh, D. M., Shannon, E. E., and Dougherty, D. M. (2007).

    Personality and Individual Differences, 43, 1333-1343.

  • Characterizing aggressive behavior with the Impulsive/Premeditated Aggression Scale among adolescents with Conduct Disorder.

    Mathias, C. W., Stanford, M. S., Marsh, D. M., Frick, P. J., Moeller, F. G., Swann, A. C., and Dougherty, D. M. (2007).

    Psychiatry Research, 151, 231-242 PubMed Icon PubMed Central - Free Full Text Icon

  • Teenagers do not always lie: Characteristics and correspondence of telephone and in-person reports of adolescent drug use.

    Shannon, E. E., Mathias, C. W., Marsh, D. M., Dougherty, D. M., and Liguori A. (2007).

    Drug and Alcohol Dependence, 90, 288-291. PubMed Icon PubMed Central - Free Full Text Icon

  • Manic symptoms and impulsivity during bipolar depressive episodes.

    Swann, A. C., Gerard Moeller, F., Steinberg, J. L., Schneider, L., Barratt, E. S., and Dougherty, D. M. (2007).

    Bipolar Disorders, 9, 206-212 PubMed Icon PubMed Central - Free Full Text Icon

  • Cannabis withdrawal among adolescent cannabis users in an outpatient research setting.

    Dawes, M. A., Liguori, A., and Dougherty, D. M. (2006).

    American Journal of Addiction, 15, 485-486. PubMed Icon

  • Immediate and Delayed Memory Tasks.

    Mathias, C. W., Marsh, D.M., and Dougherty, D. M. (2006).

    In N. J. Salkind and K. Rasmussen (Eds.), The Encyclopedia of Measurement and Statistics Vol 2. (pp. 452-453).
    Sage Publications; Thousand Oaks, California.

  • Laboratory behavioral measures of impulsivity.

    Mathias, C. W., Marsh, D.M., and Dougherty, D. M. (2006).

    In N. J. Salkind and K. Rasmussen (Eds.), The Encyclopedia of Measurement and Statistics Vol 2. (pp. 525-526).
    Sage Publications; Thousand Oaks, California.

  • Impulsivity and BOLD fMRI activation in MDMA users and healthy control subjects.

    Valdes, I. H., Steinberg, J. L., Narayana, P. A., Kramer, L. A., Dougherty, D. M., Swann, A. C., Barratt, E. S., and Moeller, F. G. (2006).

    Psychiatry Research: Neuroimaging, 147, 239-242. PubMed Icon

  • The conceptualization and role of impulsivity: Bipolar Disorder and Substance Abuse.

    Dougherty, D. M., Marsh, D. M., Mathias, C. W., and Swann, A. C. (2005).

    Psychiatric Times, 22, 32-35.

  • Laboratory behavioral measures of impulsivity.

    Dougherty, D. M., Mathias, C. W., Marsh, D. M., and Jagar, A. (2005).

    Behavior Research Methods, 37, 82-90. PubMed Icon

  • Acute yohimbine increases laboratory-measured impulsivity in normal subjects.

    Swann, A. C., Birnbaum, D., Jagar, A. A., Dougherty, D. M., and Moeller, F. G. (2005).

    Biological Psychiatry, 57, 1209-1211. PubMed Icon

  • Increased impulsivity associated with severity of suicide attempt history in patients with Bipolar Disorder. 

    Swann, A. C., Dougherty, D. M., Pazzaglia, P. J., Pham, M., Steinberg, J. L., and Moeller, F. G. (2005).

    American Journal of Psychiatry, 162, 1680-1687. PubMed Icon

  • Age at first drink relates to behavioral measures of impulsivity: The Immediate and Delayed Memory Tasks.

    Dougherty, D. M., Mathias, C. W., Lee, M. A., and Marsh, D. M. (2004).

    Alcoholism: Clinical and Experimental Research, 28, 408-414. PubMed Icon

  • Laboratory measured behavioral impulsivity relates to suicide attempt history.

    Dougherty, D. M., Mathias, C. W., Marsh, D. M., Papageorgiou, T. D., Swann, A. C., and F. G. Moeller (2004).

    Suicide and Life-Threatening Behavior, 34, 374-385. PubMed Icon

  • Overview of workshop on drug abuse and suicidal behavior.

    Erinoff, L., Anthony, J. C., Brown, G. K., Caine, E. D., Conner, K. R., Dougherty, D. M., Glowinski, A. L., Prince, R. K., Goldston, D. B., Linehan, M. M., Thompson, E. A., Mann, J. J., Miczek, K. A., Ries, R. K., Roy, A., Sher, K. J., Tarter, R. E., Wilcox, H. D., Wines, J. D., and Yen, S. (2004).

    Drug and Alcohol Dependence, 76, s3-s9. PubMed Icon

  • P300 event related potential amplitude and impulsivity in cocaine dependent subjects.

    Moeller, F. G., Barratt, E. S., Fischer, C. J., Dougherty, D. M., Reilly, E. L., Mathias, C. W., and Swann, A. C. (2004).

    Neuropsychobiology, 50, 167-173. PubMed Icon

  • Impulsivity: A link between bipolar disorder and substance abuse.

    Swann, A. C., Dougherty, D. M., Pazzaglia, P. J., Pham, M., and Moeller, F. G. (2004).

    Bipolar Disorders, 6, 204-212. PubMed Icon

  • Behavioral impulsivity paradigms: A comparison in hospitalized adolescents with disruptive behavior disorders.

    Dougherty, D. M., Bjork, J. M., Harper, R. A., Marsh, D. M., Moeller, F. G., Mathias, C. W, and Swann, A. C. (2003).

    Journal of Child Psychology and Psychiatry and Allied Disciplines, 44, 1145-1157. PubMed Icon

  • Validation of the Immediate and Delayed Memory Tasks in hospitalized adolescents with disruptive behavior disorders.

    Dougherty, D. M., Bjork, J. M., Harper, R. A., Mathias, C. W., Moeller, F. G., and Marsh, D. M. (2003).

    Psychological Record, 53, 509-532.

  • Familial transmission of continuous performance test behavior: Attentional and impulsive response characteristics.

    Dougherty, D. M., Bjork, J. M., Moeller, F. G., Harper, R. A., Marsh, D. M., Mathias, C. W., and Swann, A. C. (2003).

    Journal of General Psychology, 130, 5-21. PubMed Icon

  • Laboratory measures of impulsivity.

    Dougherty, D. M., Mathias, C. W., and Marsh, D. M. (2003).

    In E. F. Coccaro (Ed.), Aggression: Psychiatric Assessment and Treatment. Medical Psychiatric Series No. 22,
    Marcel Dekker Publishers: New York, New York.

  • Commission error rates on a continuous performance test are related to deficits measured by the Benton Visual Retention Test.

    Dougherty, D. M., Mathias, C. W., Marsh, D. M., Greve, K. W., Bjork, J. M., and Moeller, F. G. (2003).

    Assessment, 10, 3-12. PubMed Icon

  • Psychopathology among persons responding to participation as normal controls in behavioral research studies.

    Huang, D. B., Koo, H., Dougherty, D. M. and Hassan, Y. (2003).

    Comprehensive Psychiatry, 44, 83-87.

  • Impulsivity and phase of illness in bipolar disorder.

    Swann, A. C., Pazzaglia, P., Nicholls, A., Dougherty, D. M., and Moeller, F. G. (2003).

    Journal of Affective Disorders, 73, 105-111 PubMed Icon

  • The serotonin 2a receptor T102C polymorphism and impaired impulse control.

    Bjork, J. M., Moeller, F. G., Dougherty, D. M., Swann, A. C., Machado, M. A., and Hanis, C. L. (2002).

    American Journal of Medical Genetics (Neuropsychiatric Genetics), 114, 336-339. PubMed Icon

  • Possible amotivational effects following marijuana smoking under laboratory conditions.

    Cherek, D. R., Lane, S. D., and Dougherty, D. M. (2002).

    Experimental & Clinical Psychopharmacology, 10, 26-38. PubMed Icon

  • Immediate and Delayed Memory Tasks: A computerized behavioral measure of memory, attention and impulsivity.

    Dougherty, D. M., Marsh, D. M., Mathias, C. W., and Steinberg, J. L. (2002).

    Behavior Research Methods, Instruments, & Computers, 34, 391-398. PubMed Icon

  • Laboratory measures of impulsivity: A comparison of women with and without childhood aggression.

    Mathias, C. W., Dougherty, D. M., Marsh, D. M., Moeller, F. G., Hicks, L. R., Dasher, K., and Bar-Eli, L. (2002).

    The Psychological Record, 52, 289-303.

  • Laboratory-measured aggressive behavior of women: Acute tryptophan depletion and augmentation

    Marsh, D. M., Dougherty, D. M., Moeller, F. G., Swann, A. C., and Spiga, R. (2002).

    Neuropsychopharmacology, 26, 660-671. PubMed Icon

  • Comparison of women with high and low trait impulsivity using laboratory impulsivity models of response-disinhibition and reward-choice.

    Marsh, D. M., Dougherty, D. M., Mathias, C. W., Moeller, F. G., and Hicks, L. R. (2002).

    Personality and Individual Differences, 33, 1291-1310.

  • Impulsivity and substance abuse: What is the connection?

    Moeller, F. G., and Dougherty, D. M. (2002).

    Addictive Disorders and Their Treatment, 1, 2-10.

  • Heavy “Ecstasy” use is associated with increased impulsivity.

    Moeller, F. G., Dougherty, D. M., Steinberg, J. L., Swann, A. C., Silverman, P. B., Ruiz, P., and Barratt, E. S. (2002).

    Addictive Disorders and Their Treatment, 1, 47-52.

  • Two models of impulsivity: Relationship to personality traits and psychopathology.

    Swann, A. C., Bjork, J. M., Moeller, F. G., and Dougherty, D. M. (2002).

    Biological Psychiatry, 51, 988-994. PubMed Icon

  • Endogenous plasma testosterone levels and commission errors in women: A preliminary report.

    Bjork, J. M., Moeller, F. G., Dougherty, D. M., and Swann, A. C. (2001).

    Physiology and Behavior, 73, 217-221.

  • The impact of impulsivity on cocaine use and retention in treatment.

    Moeller, F. G., Dougherty, D. M., Barratt, E. S., Schmitz, J. M., Swann, A. C., and Grabowski, J. (2001).

    Journal of Substance Abuse Treatment,21, 193-198.

  • Measurement of inter-episode impulsivity in bipolar disorder.

    Swann, A. C., Anderson, J., Dougherty, D. M., and Moeller, F. G. (2001).

    Psychiatry Research, 101, 195-197.

  • Effects of Moderate and High Doses of Alcohol on Attention, Impulsivity, Discriminability, and Response Bias in Immediate and Delayed Memory Task Performance.

    Dougherty, D. M., Marsh, D. M., Moeller, F. G., Chokshi, R. V., and Rosen, V. C. (2000).

    Alcoholism: Clinical and Experimental Research, 24, 1702-1711.

  • A comparison between adults with conduct disorder and normal controls on a Continuous Performance Test: Differences in impulsive response characteristics.

    Dougherty, D. M., Bjork, J. M., Marsh, D. M., and Moeller, F. G. (2000).

    The Psychological Record, 50, 203-219.

  • A Test of the psychometric characteristics of the BIS-Brief among three groups of youth

    Mathias, C. W., Stanford, M. S., Liang, Y., Goros, M., Charles, N. E., Sheftall, A. H., Mullen, J., Hill-Kapturczak, N., Acheson, A., Olvera, R. L., and Dougherty, D. M. (in press).

    Psychological Assessment.